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- Huang M, Akerberg AA, Zhang X, Yoon H, Joshi S, Hallinan C, Nguyen C, Pu WT, Haigis MC, Burns CG, Burns CE. Intrinsic myocardial defects underlie an Rbfox-deficient zebrafish model of hypoplastic left heart syndrome. Nat Commun. 2022. 5;13(1):5877. PMID: 36198703
- Yoon H*, Shaw JL*, Haigis MC, Greka A. Lipid metabolism in sickness and in health: emerging regulators of lipotoxicity. Mol Cell. 2021. 16;81(18):3708-3730. PMID: 34547235 [* co-first author]
- Lim HJ*, Yoon H*, Kim H*, Kang YW, Kim JE, Kim OY, Lee EY, Twizere JC, Rak J, Kim DK. Extracellular vesicle proteomes shed light on the evolutionary, interactive, and functional divergence of their biogenesis mechanisms. Frontiers Cell and Developmental Biology. 01 October 2021. https://doi.org/10.3389/fcell.2021.734950 [online publish] [* co-first author]
- Zaganjor E, Yoon H, Spinelli JB, Nunn ER, Laurent G, Keskinidis P, Sivaloganathan S, Joshi S, Notarangelo G, Mulei S, Chvasta MT, Tucker SA, Kalafut K, van de Ven RAH, Clish CB, Haigis MC. SIRT4 is an early regulator of branched-chain amino acid catabolism that promotes adipogenesis. Cell Rep. 2021. 36(2):109345. PMID: 34260923
- Wong SJ, Ringel AE, Yuan W, Paulo JA, Yoon H, Currie MA, Haigis MC. Development of a colorimetric a-ketoglutarate detection assay for prolyl hydroxylase domain (PHD) proteins. J Biol Chem. 2021. 100397. PMID: 33571527
- Ringel AE, Drijvers JM, Baker GJ, Catozzi A, García-Cañaveras JC, Gassaway BM, Miller BC, Juneja VR, Nguyen TH, Joshi S, Yao C, Yoon H, Sage PT, LaFleur MW, Trombley JD, Jacobson CA, Maliga Z, Gygi SP, Sorger PK, Rabinowitz JD, Sharpe AH, Haigis MC. Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity. 2020. 183(7):1848-1866. PMID: 33301708
- Yoon H, Spinelli JB, Zaganjor E, Wong SJ, German NJ, Randall EC, Dean A, Clermont A, Paulo JA, Garcia D, Li H, Wang Y, Agar NR, Goodyear LJ, Shaw RJ, Gygi SP, Auwerx J, Haigis MC. PHD3 loss promotes exercise capacity and fat oxidation in skeletal muscle. Cell Metabolism. 2020. 32(2):215-228.e7. PMID: 32663458
- Randall EC, Lopez BGC, Peng S, Regan MS, Abdelmoula WM, Basu SS, Santagata S, Yoon H, Haigis MC, Agar JN, Tran NL, Elmquist WF, White FM, Sarkaria JN, Agar NYR. Localized metabolomic gradients in patient-derived xenograft models of glioblastoma. Cancer Res. 2020. 80(6):1258-1267. PMID: 31767628
- Gonzalez Herrera KN, Zaganjor E, Ishikawa Y, Spinelli JB, Yoon H, Lin JR, Satterstrom FK, Ringel A, Mulei S, Souza A, Gorham JM, Benson CC, Seidman JG, Sorger PK, Clish CB, Haigis MC. Small-molecule screen identifies de novo nucleotide synthesis as a vulnerability of cells lacking SIRT3. Cell Rep. 2018. 22(8):1945-1955. PMID: 29466723
- Kang J*, Shin SH*, Yoon H*, Huh J, Shin HW, Chun YS, Park JW. FIH is an oxygen sensor in ovarian cancer for G9a/GLP-driven epigenetic regulation of metastasis-related genes. Cancer Res. 2018. 78(5):1184-1199. PMID: 29259012 [* co-first author]
- Spinelli JB, Yoon H, Ringel AE, Jean-Favre S, Clish CB, Haigis MC. Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass. Science. 2017. 358(6365):941-946. PMID: 29025995
- Malone CF, Emerson C, Ingraham R, Barbosa W, Guerra S, Yoon H, Liu LL, Michor F, Haigis MC, Macleod KF, Maertens O, Cichowski K. mTOR and HDAC inhibitors converge on the TXNIP/thioredoxin pathway to cause catastrophic oxidative stress and regression of RAS-driven tumors. Cancer Discovery. 2017. 7(12):1450-1463. PMID: 28963352
- German NJ, Yoon H, Yusuf RZ, Murphy JP, Finley LW, Laurent G, Haas W, Satterstrom FK, Guarnerio J, Zaganjor E, Santos D, Pandolfi PP, Beck AH, Gygi SP, Scadden DT, Kaelin WG Jr, Haigis MC. PHD3 loss enables reliance on fat oxidation via deactivation of acetyl-CoA carboxylase. 2016. Mol Cell. 63:1006-1020. PMID: 27635760
- Shin DH, Choi YJ, Jin P, Yoon H, Chun YS, Shin HW, Kim JE, Park JW. Distinct effects of SIRT1 in cancer and stromal cells on tumor promotion. Oncotarget. 2016. 7(17):23975-87. PMID: 26992208
- Lee M, Kim DW, Yoon H, So D, Khalmuratova R, Rhee CS, Park JW, Shin HW. Sirtuin 1 attenuates nasal polypogenesis by suppressing epithelial-to-mesenchymal transition. J Allergy Clin Immunol. 2016. 137(1):87-98.e7. PMID: 26342525
- Yoon H, Kim HL, Chun YS, Shin DH, Lee KH, Shin CS, Lee DY, Kim HH, Lee ZH, Ryoo HM, Lee MN, Taeg Oh G, Park JW. NAA10 controls osteoblast differentiation and bone formation as a feedback regulator of Runx2. Nat Commun. 2014. 5:5176. PMID: 25376646
- Shin SH, Yoon H, Chun YS, Shin HW, Lee MN, Oh GT, Park JW. Arrest defective 1 regulates the oxidative stress response in human cells and mice by acetylating methionine sulfoxide reductase A. Cell Death Dis. 2014. 5:e1490. PMID: 25341044
- Kim HJ, Park JW, Yoon H, Shin DH, Lee ZH, Kim HH, Lee KH, Ju UI, Seok SH, Seung Lim, Chun YS. Plant homeodomain finger protein 2 promotes bone formation by demethylating and activating Runx2 for osteoblast differentiation. Cell Res. 2014. 24(10):1231-49. PMID: 25257467
- Yoon H, Shin SH, Shin DH, Chun YS, Park JW. Differential roles of Sirt1 in HIF-1α and HIF-2α mediated hypoxic responses. Biochem Biophys Res Commun. 2014. 444(1):36-43. PMID: 24423936
- Yoon H, Lim JH, Cho CH, Huang LE, Park JW. CITED2 controls the hypoxic signaling by snatching p300 from the two distinct activation domains of HIF-1α. Biochim Biophys Acta. 2011. 1813(12):2008-16. PMID: 21925214
- Lee YM, Lim JH, Yoon H, Chun YS, Park JW. Antihepatoma activity of chaetocin due to deregulated splicing of hypoxia-inducible factor 1α pre-mRNA in mice and in vitro. Hepatology. 2011. 53(1):171-80. PMID: 21140472
